The old Mayfair Hotel was allegedly broken into last week.
Jersey Police want to speak to anyone who saw or heard anything suspicious in the area between 10:30pm and 11:30pm on Thursday 10 February.
Officers are particularly keen to speak to anyone living nearby who might have noticed something unusual, including any vehicles.
Anyone with relevant information is asked to call the police on 612612 or Crimestoppers anonymously on 0800 555 111.
The old hotel is on St Saviour's Road. It closed at the end of October 2021.